Hume is often grouped with John Locke George Berkeley and a handful of others as a British Empiricist. Beginning with his A Treatise of Human Nature (1739) Hume strove to create a total naturalistic "science of man" that examined the psychological basis of human nature. In stark opposition to the rationalists who preceded him most notably Descartes he concluded that desire rather than reason governed human behaviour saying:

"Reason is and ought only to be the slave of the passions".

A prominent figure in the sceptical philosophical tradition and a strong empiricist he argued against the existence of innate ideas concluding instead that humans have knowledge only of things they directly experience.